Island House in Key West calls itself the best gay resort in the world: a clothing-optional sanctuary for gay men since 1976, on the town's gay Guesthouse Row in Old Town, at the corner of Fleming and White Streets, about a twelve-minute walk from Duval Street. Guests can disrobe as soon as they enter the front door, throughout the clothing-optional side of the resort, and the resort describes itself as a playground for committed couples, couples that play, singles looking to mingle and those who prefer to watch.

It has a pool and sundecks, a bar and cafe, and a 24-hour health club and spa with a gym, a steam room, a dry sauna, two large Jacuzzis and a five-man shower, plus massages. Rooms range from standard rooms to villas and apartments, and there is a Sunday naked pool party.